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🚿 Clear drains, zero stress—join the clean pipe revolution!
Zep Drain Defense Enzymatic Drain Cleaner Powder is a 16 oz. concentrated formula designed to safely and effectively break down organic buildup in slow drains. Offering up to 40 treatments, it uses natural enzymes to digest gunk over a few nights, ensuring long-term pipe health without harsh chemicals. Safe for all plumbing and septic systems, this unscented powder is perfect for proactive maintenance and restoring optimal water flow.






















| ASIN | B000AXDLAI |
| Best Sellers Rank | #14,133 in Health & Household ( See Top 100 in Health & Household ) #14 in Septic Tank Treatments |
| Brand Name | Zep |
| Customer Reviews | 4.3 4.3 out of 5 stars (1,951) |
| Global Trade Identification Number | 00021709500165 |
| Included Components | Zep Drain Care Build-Up Remover Powder 18 Ounces ZDC16 |
| Item Type Name | Zep Drain Care Build-Up Remover Powder 18 Ounces ZDC16 |
| Item Weight | 0.55 Pounds |
| Liquid Volume | 18 Fluid Ounces |
| Manufacturer | Zep |
| Product Benefits | Prevents clogs and maintains clean pipes with enzyme-based formula |
| Scent | Unscented |
| UPC | 021709500165 021709015720 |
| Unit Count | 18.0 Ounce |
| Warranty Description | Warranty |
R**.
Great Product!!! These enzymes are hungry!!! Totally clear drain.
This product works great!! You have to follow the instructions, and use it for 3 nights straight, otherwise it may not work. I didn't fully understand about the drain cleaners till now. Some are meant to power through pipes and cut a hole through the gunk and have your drain open up and let the water flow through - like Liquid Plumber Gel, which are more like a strong acid to burn their way through. Enforcer DC16 is an enzyme based drain cleaner which actually eats away at the gunk in your drain, which takes a bit of time. Once it eats away all the gunk - your pipes are totally CLEAN and water flows great. That's why it takes 3 nights (of eating) especially when you haven't done this in a long time. I used this in my kitchen sink and bathtub drain for 3 nights. My kitchen drain was running just okay, so I used a plunger just like 3 times, and then suddenly the kitchen drain ran beautifully. However, then the bathtub drain completely closed and I was shocked at how much gunk came up - more than I ever saw. What apparently happened was that the enzymes ate the walls of the pipes (drain) and cleared off all of the gunk in the pipes but it overwhelmed the drain pipe, and now no water was going down. I put in a half of a bottle of the Liquid Plumber Gel, and it took almost one hour before the Gel (acid) burned through and the water then completely went down, and ever since the drain is the best it has been in a long time. Water flows down very well. The enzyme cleaner hasn't just made a hole in the gunk, but actually cleaned it out, which is what an enzyme cleaner does. Fantastic!!! Now, I just have to do the maintenance scoops every month or two months and the drains will be fine. It's really easy to use also. Just put the scoop in hot water in a 16 oz jar, and put in the drain at night - 3 nights in a row. I think it's always best to run some hot water in the drain - about 1 minute, prior to putting the enzyme down for the best results. I looked at other enzyme cleaners, and some are in liquid form. It's definitely more expensive (paying for convenience and water). This is actually very convenient with the scoop inside. It's cheaper, very effective, and takes up less space. All I know is that this works fantastic. You just have to be patient for the 3 nights, and you might need something like Liquid Plumber Gel the first time you do this, (and a plunger) if you never did this before, and there is lots of hair, gunk, grease etc. in your pipes, and it takes all of this off your pipes for the first time.
T**V
Works. Not sealed. Might get messy.
Worked great. 2 cups of warm water (1 solo cup) + 1 scoop does the trick. Does not come sealed so if your package gets mishandled, you’ll have a huge mess on your hands. Maybe buy at a physical store if your delivery drivers play bowling with your packages.
B**P
Good when used a monthly preventative measure
I use this monthly at night before I go to bed to keep my drains running free. Has been an improvement in reducing buildup in my pipes. I prefer the enzymatic preventative approach to using harsh drain openers and I have had success with keeping the drains running well.
J**F
This stuff works!
I moved into my new-older home a few months ago. I had smelly drains in my house and out in the shop, plus I had one slow drain. One application in each drain solved all the issues. I am amazed and very happy with the results. I’m glad I found this product.
A**R
Excellent drain cleaner
Excellent product keeps drains clean
M**A
no scoop
insructions says 1 scoop per 16 oz. OK how big is a scoop? entire container is 18 oz. diveded by 28 [number of uses] that equals .642 oz. I don't have a small scale. how about making 28 equal piles on the table. OR how about a scoop shipped in container? OR how many table spoons. OR ml. Or mabye an old coffee scoop like I am going to try[1/8 cup].Zep customer service number on container does not seem to work. If this is same as old enzym powder it works great for natural oils like olive,cooking and soap.
C**Z
Breaks down fatbergs but get ready to deal with that
It really works but it takes weeks or months to see results. It actually caused more clogs in the beginning because it was breaking down fat bergs that were rock solid from decades of buildup, so I had to snake them out of the sewer trap to unclog the system again. The best way I can describe it is the enzymes causes the fatbergs to “cave in” and this can cause a clog. These fatbergs are so hard, drain cleaners likely won’t work, you’ll probably need a snake. After a few more times of snaking the clogs from the enzyme breaking down the fat bergs, the pipes are running smoother than ever. I strongly recommend you prepare yourself to snake if your pipes are over 50 years old, because this enzyme will definitely break down the fat buildup which can result in more clogs in the first few months.
S**C
Does not work to clear slow drain
Did not work on Kitchen Sink / Disposal. No change after repeated applications. Same as @Amina O "This doesn't work at all."
A**H
No amount of cleaners or bleach could get rid of the smell coming from our bathroom drain. Couple doses of this stuff and it’s good as new. Highly recommended!
Trustpilot
4 days ago
2 weeks ago